Definition

Intrinsic factor is a protein produced by glands in the stomach lining. It is necessary for the absorption of vitamin B-12 by the intestines.

A deficiency in intrinsic factor can cause pernicious anemia. Such deficiencies can be caused by surgical removal of the stomach, inherited conditions, or other diseases.

Lots More Information:
•Vitamin B12
•Pernicious anemia
Review Date:7/29/2005
Reviewed By: Paul B. Tabereaux, M.D., M.P.H., Division of Cardiovascular Diseases, Department of Internal Medicine, University of Alabama School of Medicine, Birmingham, AL. Review provided by VeriMed Healthcare Network.