Definition
Morphine overdose is poisoning from an overdose of morphine.
Poisonous Ingredient
Morphine sulfate
Where Found
- Morphine
- M S Contin
- Roxanol
- Astramorph
Note: This list may not be all-inclusive.
Symptoms
- Body as a whole
- Respiratory
- Difficulty breathing
- Slow and labored breathing
- Shallow breathing
- No breathing temporarily
- Eyes, ears, nose, and throat
- Pinpoint pupils
- Skin
- Gastrointestinal
- Spasms of the stomach or intestinal tract
- Nausea
- Vomiting
- Constipation
- Heart and blood vessels
- Weak pulse
- Low blood pressure
- Palpitations
- Nervous system
Home Treatment
- DO NOT INDUCE VOMITING.
- Perform mouth-to-mouth breathing if the person stops breathing.
Before Calling Emergency
Determine the following information:
- The patient's age, weight, and condition
- The name of the product (ingredients and strengths if known)
- The time it was swallowed
- The amount swallowed
- If the medication was prescribed for the patient
Poison Control, or a local emergency number
They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.
What to expect at the emergency room
Some or all of the following procedures may be performed:
- Use gastric lavage.
- Administer activated charcoal.
- Administer a laxative.
- Give a counteracting drug (narcotic antagonist). Multiple doses may be needed.
- Administer intravenous fluids as needed.
- Monitor breathing.
- Treat the symptoms.
- Naloxone hydrochloride intravenously.
Expectations (prognosis)
If an antidote can be given, recovery from an acute overdose occurs within 24 - 72 hours.
Review Date:5/10/2005
Reviewed By: William D. Whetstone, M.D., Division of Emergency Medicine, University of California San Francisco, San Francisco, CA. Review provided by VeriMed Healthcare Network.

Reviewed By: William D. Whetstone, M.D., Division of Emergency Medicine, University of California San Francisco, San Francisco, CA. Review provided by VeriMed Healthcare Network.


