A uterine fibroid (known medically as a leiomyoma or myoma) is a benign (noncancerous) growth composed of smooth muscle and connective tissue. The size of a fibroid varies from that of a pinhead to larger than a melon. Fibroid weights of more than 20 pounds have been reported.
Fibroids originate from the thick wall of the uterus and are categorized by the direction in which they grow:
- Intramural fibroids grow within the middle and thickest layer of the uterus (called the myometrium). They are the most common fibroids.
- Subserosal fibroids grow out from the thin outer fibrous layer of the uterus (called the serosa). Subserosal can be either stalk-like (pedunculated) or broad-based (sessile). These are the second most common fibroids.
- Submucous fibroids grow from the uterine wall toward and into the inner lining of the uterus (the endometrium). Submucous fibroids can also be stalk-like or broad-based. Only about 5% of fibroids are submucous.

The Female Reproductive SystemThe Primary Organs and Structures in the Reproductive System The primary structures in the reproductive system are as follows:
The inner lining of the uterus is called the endometrium, and during pregnancy it thickens and becomes enriched with blood vessels to house and support the growing fetus. If pregnancy does not occur, the endometrium is shed as part of the menstrual flow. Menstrual flow also consists of blood and mucus from the cervix and vagina. Reproductive Hormones The hypothalamus (an area in the brain) and the pituitary gland regulate the reproductive hormones. The pituitary gland is often referred to as the master gland because of its important role in many vital functions, many of which require hormones. In women, six key hormones serve as chemical messengers that regulate the reproductive system:
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